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Fırat Tıp Dergisi
2017, Volume 22, Number 1, Page(s) 043-044
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A Case of Progressive Multifocal Leukoencephalopathy During Chronic Lymphocytic Leukemia
Çetin Kürşad AKPINAR1, Emrah AYTAÇ2, Sibel ÇELİKER USLU1, Alper ARSLAN1, Bilge PİRİ ÇINAR1
1Samsun Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, Samsun, Türkiye
2Fırat Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Elazığ, Türkiye

Latent John Cunningham virus reactivates in immunosuppressed individuals and rarely it can cause Progressive Multifocal Leukoencephalopathy. 67-year-old male patient was admitted to the emergency service with a complaint of seizure and he was given diazem and phenytoin therapy with a diagnosis of status epilepticus. Chronic lymphocytic leukaemia in remission was found in his anamnesis. Lesion that could be compatible with Multifocal Leukoencephalopathy was detected in brain magnetic resonance imaging with contrast, perfussion magnetic resonance imaging and magnetic resonance spectroscopy. The case died in the fifth month of follow-up. This article has presented a case of rare Progressive Multifocal Leukoencephalopathy in the course of chronic lymphocytic leukaemia.

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