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Fırat Tıp Dergisi
2018, Cilt 23, Sayı 3, Sayfa(lar) 146-150
[ Turkish ] [ Tam Metin ] [ PDF ]
Effects of Metabolic Compositions on the Development of Diabetic Foot Ulcers
Kader UĞUR, Abdullah Mübin ÖZERCAN
1Fırat Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı Endokrinoloji Bilim Dalı, Elazığ, Türkiye
2Fırat Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı Gastroenteroloji Bilim Dalı, Elazığ, Türkiye

Objective: Diabetes has become epidemic not only in our country but also all over the world. Foot ulcers in diabetic patients should be considered not only as an ulcer or a complication of diabetes but also as changes in the metabolic composition of the body. Therefore, it is aimed, to compare the demographic characteristics, anthropometric measurements and some biochemical parameters of healthy controls, diabetic foot ulcer patients (DFUP) and nonulcer diabetic patients (NUDP) in this study.

Material and Method: A total of 90 individuals, 26 DFUP, 34 NUDP and 30 healthy controls were included. The DFUP group was evaluated according to the Wagner classification.Body mass index (BMI), neck, waist and hip circumference, fasting blood sugar level, HbA1c, lipid profile, aspartat aminotransferase (AST), alanin aminotransferase (ALT), albumin, urea and creatinine levels were obtained from patient database and body composition analysis was detected by using TANITA device.

Results: It is reported that proportion of fat was 27.4% in DFUP group, 33.9% in the NUDP group and 22.3% in the control group. Lipid profile measures in the DFUP group were significantly lower than the other two groups. It is observed that in the DFUP group, the Wagner score increases as the BMI (p =0,452), waist circumference (p =0,848) and hip circumference (p =0,614) decreases. Also, in DFUP patients, an increase in the amount of urea and decrease in the albumin were reported.

Conclusion: Decrease in fat, albumin and lipid profile measures and increase in urea levels in DFUP patients indicate that these parameters play a role in the etiopathology of this disease. Therefore, we conclude that keeping the body fat composition close to ideal values in the diabetic patient group may have a protective role against DFUP formation.


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