Objective: To investigate the role of Neutrophil-Lymphocyte ratio (NLR), Lymphocyte-Monocyte ratio (LMR), Platelet-Lymphocyte ratio (PLR), Mean Platelet Volume (MPV), C- reactive protein (CRP) values in determining of the time until delivery after preterm premature rupture of membranes (PPROM).

Material and Method: The study data were collected from the hospital records between January 2017 and December 2018. The patients with pprom, below 34 weeks of gestation were included in the study. The CRP, NLR, LMR, PLR and MPV values of the patients were obtained from the blood sample taken at the first admission before antibiotic prophylaxis and betamethasone dose for lung maturation. The patients were divided into two groups; the patients in group 1 were defined as those who started spontaneous delivery in the first 72 hours, and the ones in group 2 as those who started spontaneous delivery after 72 hours. The two groups were compared in terms of their CRP, NLR, LMR, PLR and MPV values.

Results: The study included 172 patients who met the inclusion criteria. There was no significant difference between the two groups in terms of PLR and MPV values. CRP, NLR and LMR mean values of group I and group II were calculated as (1.08; 6.68; 3.00 and 0.75; 4.74; 4.07) respectively (p =0.012, p =0.001, p =0.001 ).

Conclusion: In the patients with pprom, high NLR, CRP and low LMR values may be helpful to predict delivery within 72 hours and provide appropiate patient counseling. CRP, Inflammatory Marker, Leukocyte, Preterm Premature Rupture of Membranes (PPROM).