Objective: Postoperative nausea and vomiting (PONV) is common in laparoscopic bariatric surgeries (LBS). The aim of this study is to investigate the effect of muscle relaxant antagonists on PONV seen in the recovery unit by morbidly obese patients undergoing LBS.

Material and Method: With the approval of the University Ethics Committee, the files and e-archive records of morbidly obese patients who had LBS were examined, and their demographic data, PONVscore (1: No nausea-vomiting, 2: Nausea, 3: Retching, 4: Vomiting), amount of antiemetic administered in the recovery unit were recorded. According to the muscle relaxant antagonist drugs administered at the end of the surgery, the patients were divided into the neostigmine group (GrupNEO) and the sugammadex group (GrupSUG).

Results: A total of 206 patients were included in the study and 80 of the patients were male and 126 were female. There was no statistically significant difference between the groups when the PONV score was evaluated (p >0,05). PONV that occurred by the patients in the recovery unit was 58,16% (57/98) in GroupNEO and 50% (54/108) in GroupSUG, and there was no statistical difference (p >0,05). Regarding the metoclopramide administered in the recovery unit, the dose was lower in GroupSUG than in GroupNEO, and the difference was statistically significant (p ˂0,05).

Conclusion: In our study, in which we compared the effects of muscle relaxant antagonists on the incidence of PONV after LBS in morbidly obese patients, it was observed that while less PONV was observed in the postoperative recovery unit with the use of sugammadex, there was a significant decrease in the dose of antiemetic used.