Objective: In this study, it was aimed to investigate the clinical features of COVID-19 patients hospitalized in our hospital and mortality-associated risk factors for patients who developed mortality.

Material and Method: In this retrospective study, adult patients (over 18 years of age) who were hospitalized wtih a preliminary diagnosis of COVID-19 and SARS-CoV-2 PCR test positive between October 1, 2021 - March 31, 2022, were examined. Demographic data, comorbidities, SARS-CoV-2 vaccination history, laboratory and radiological data at first admission, need for intensive care, need for mechanical ventilation, and mortality rates during hospitalization were analyzed. The risk factors for mortality were investigated by multivariate logistic regression analysis.

Results: The median age of the 266 patients included in the study was 72 (23-97) , and 142 (53.4%) were male. There was at least one comorbidity in 238 (89.4%) of the patients. Mortality developed during hospitalization in 58 (21.8%) patients. In logistic regression analysis, age (p :0.022, OR :1.108, 95% CI :1.1015-1.211), CAD (p :0.005, OR :3.121, 95% CI :1.411-6.904), CRF (p :0.001, OR :5.674, 9%5 CI :1.956-16.463) was found to be an independent risk factor for mortality, and the number of doses of SARS-CoV-2 vaccine (p <0.001, OR :0.535, 95% CI :0.388-0.739) was found to be a protective factor from mortality.

Conclusion: Significant mortality rates can be seen in the course of COVID-19. It is important to identify patients who may develop a poor prognosis in the early period. In our study, advanced age, CAD and CRF comorbidities, and the number of SARS-CoV-2 vaccine doses were determined as independent risk factors for mortality.