Objective: The most common cause of chronic liver disease in our country is chronic viral hepatitis due to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Human immunodeficiency virus (HIV) can affect all segments of the society, shorten the healthy life time, and spread from person to person. In this study; It is aimed to retrospectively analyze the results of routine hepatitis and HIV serology tests studied on patient serum samples sent from various clinics and polyclinics to the microbiology laboratory of our hospital in 2021 and contribute to the creation of up-to-date regional data by evaluating the test results, taking protective measures and raising the awareness of health personnel at risk.

Material and Method: Hepatitis B surface antigen (HBsAg), HCV antibody (Anti-HCV) and HIV antibody (Anti-HIV) and Hepatitis B surface antibody (Anti-HBs) tests; was performed on the Cobas e601 (Roche Diagnostics, Germany) using the electrochemiluminescence immunoassay method.

Results: In the study, 533 (5.3%) of 10,003 samples submitted for HBsAg, 105 (1.1%) of 9,996 samples evaluated for Anti-HCV, and 4,260 (42.6%) of 9,994 samples tested for Anti-HBs were seropositive. Of the 9,952 samples sent for anti-HIV, 133 (1.3%) were reactive and as a result of the confirmation tests, positivity was found in 72 (0.7%) samples.

Conclusion: Continuity of screening of risk groups for these infections should be ensured by raising social awareness in the prevention of HBV, HCV and HIV infections.