Results: Methicillin susceptibility of Staphylococcus aureus strains were determines as 49% and ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin susceptibilities were found as 52%, 55%, 56% and 60%, respectively. Efficacy of the studied agents were not statistically significant (p=0.211, 0.123, 0.169, 0.075, respectively).

Conclusion: The studied quinolones were determined as moderately active to Staphylococcus aureus strains. Instead of for using new generation quinolones to methicillin resistant strains which have a wide spectrum resistance to both beta-lactam and non-beta-lactam antibiotics, particularly, it will be more appropriate to use them in non-life threatening infections caused by methicillin susceptible strains. ©2006, Fırat Üniversitesi, Tıp Fakültesi