Fascioliasis is a zoonotic infection caused by Fasciola hepatica. We report a 27-year-old female patient with chronic cholecystitis due to Fasciola hepatica. Abdominal ultrasonography, CT scan and laboratory findings were normal except eosinophilia. The final diagnosis was made macroscopic and serologic findings. It must be remembered that fascioliasis is an exceptional cause of chronic cholecystitis.