Objective: H1N1 pandemic which is the first pandemic of 21st century has currently affected worldwide including our country. The aim of the present research was to analyze the clinical, laboratory and radiological characteristics of 46 confirmed cases who were hospitalized with H1N1 influenza in our clinic.

Materials and Methods: Among probable patients for H1N1, 46 confirmed cases who tested positive for the H1N1 virus by real-time PCR were included in present study. All of them were treated with oseltamivir while patients suggested bacterial superinfection were also treated with antibiotics.

Results: Thirty (65%) were females; six were pregnant and 10 (22%) were imported cases. They aged between 17 and 58 years old (median: 30,65±10,21). Fever, cough, sore throat and myalgia were the most frequent symptoms. The median time from the onset of illness to hospital admission was three days. Most of patients had diffuse bilateral pulmonary infiltrates in chest X-rays. Four patients had been admitted to an intensive care unit (ICU); three (7%) of them died; all of them had an underlying disease. Twenty three (50%) patients received antibiotics in addition to oseltamivir.

Conclusion: The influenza A pandemic due to novel H1N1; mostly affected children, young adults, healthy people and pregnants in Turkey as other countries. The hospitalization rates rised due to severe pneumonia and need for ICU. Severe course and death were seen especially in patients who had underlying disease. Therefore, risky groups should be vaccinated, public should be informed about measures which will prevent contamination like hand washing.