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Fırat Tıp Dergisi
2015, Cilt 20, Sayı 1, Sayfa(lar) 019-024
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Comparison of Histopathological Results of Thinprep and Conventional Cervicovaginal Smears
Remzi ATILGAN1, Gökhan ARTAŞ2, Selçuk KAPLAN1, Zehra Sema ÖZKAN1, Salih Burçin KAVAK1, Behzat CAN1, İbrahim Hanifi ÖZERCAN2, EKREM SAPMAZ1
1Fırat Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Elazığ, Türkiye
2Fırat Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Elazığ, Türkiye

Objective: The comparison of colposcopy results of epithelial cell abnormalities that were detected at automatic thinprep systems (TIS) and conventional cervicovaginal smears.

Material and Method: Colposcopic evaluation and biopsy were made to 145 patients that were diagnosed as epithelial cell abnormality according to the 2001 Bethesda system (TBS III) between August 2011- December 2013. Fifty-four of these patients were evaluated by TIS and the remaining 91 by conventıonal cervıcovagınal smear. We evaluated and compared the positive diagnosis rates of histopathological examination results.

Results: In TIS group, 56% positivity was identified in patients with ASCUS, 50% in ASC-H, 66% in LSIL and 100% in HSIL. The most severe pathology in patients with ASCUS was CIN-3, micro-invasive carcinoma in LSIL, invasive cervical carcinoma in HSIL. Only an AGUS case was in this group and the pathology result was chronic cervicitis. In conventıonal cervıcovagınal smears group, 35% positivity was identified in patients with ASCUS, 60% in ASC-H, %73 in LSIL and %100 in HSIL. The most severe pathology in patients with ASCUS was CIN-3, micro-invasive carcinoma in LSIL, invasive cervical carcinoma in HSIL. Four AGUS cases were in this group and their pathology results were chronic cervicitis.

Conclusion: Severe dysplasia can be found with ASCUS as ASC-H, LSIL and HSIL at that were detected with TIS and conventional cervicovaginal smears. The positivity rate of ASCUS was found a higher The at TIS than conventıonal cervicovaginal smears. Therefore we suggest colposcopic examination and if necessary biopsy for these patients.


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