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Fırat Tıp Dergisi
2015, Cilt 20, Sayı 4, Sayfa(lar) 206-209
[ Turkish ] [ Tam Metin ] [ PDF ]
Evaluation of MPV and PCT Parameters in Children with Acute Rheumatic Fever
Muhammed KARABULUT, Erdal YILMAZ
Fırat Üniversitesi Tıp Fakültesi, Çocuk Kardiyoloji Bilim Dalı, Elazığ, Türkiye

Objective: The aim of this study was to show whether mean platelet volume (MPV) and platelet-crit (PCT) were useful tools for determining and following up inflammation during the acute phase and follow-up after treatment in patients with acute rheumatic fever (ARF) compared to the healthy group.

Material and Method: 47 children with ARF and 40 healthy children were included in the study. Platelet indices and inflammatory parameters were measured for all children. Platelet indices of acute and remission phase of the disease were compared with the values of healthy children.

Results: It was not detected statistically significant differences between children with ARF and healthy children with respect to age, gender and body mass index. MPV value in ARF group was lower than the healthy group. However, the detected this decrease was not statistically significant (p=0.177). PCT value was significantly higher in children with ARF (p<0.001). By the children with ARF it was determined that white blood cells count and platelet count (PLT) values have shown a significant increase, while hemoglobine values determined also significant decrease (p<0.001 for all parameters). It was not detected a significant difference between MPV values of acute and remission phase in the patients with ARF. PCT and PLT values in the both acute and remission phase by the patients with ARF were significantly higher compared the healthy group (p=0.021, p=0.015; p=0.006, p=0.029, respectively).

Conclusion: We consider that PCT as well as PLT may be used as valuable parameters in follow-up of patients diagnosed with ARF.


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