This study presents the results of a rehabilitation program in a spastic hemiparetic subject who had undergone hemispherectomy because of Sturge- Weber syndrome and intractable epilepsy. Sturge-Weber syndrome includes unilateral cerebral cortical angiomatosis, which often leads to progressive cerebral dysfunction and epileptic seizures that are medically difficult to control. A three-year-old girl who was followed-up for 2.5 years after a diagnosis of Sturge-Weber syndrome, intractable epilepsy and right spastic hemiparesis was hospitalized at the Department of Neurosurgery for epilepsy surgery since the frequency of her seizures had increased. The functional status and quality of life of our subject, whose seizures disappeared after hemispherectomy, improved after the rehabilitation program. ©2004, Fırat Üniversitesi, Tıp Fakültesi