Objective: There ara studies in the literature on the relationship between Obsessive Compulsive Disorder (OCD) and inflammation. Neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) calculations are clinical biomarkers of peripheral inflammation that are both cost effective and readily available in the circulatory system. The monocyte lymphocyte ratio (MLR) value has also recently started to be shown as an inflammatory marker. We aimed to examine the relationship between OCD and inflammation markers such as NLR, PLR and MLR.

Material and Method: Our study is a retrospective study. Sociodemographic data and hemogram parameters of 50 patients diagnosed with OCD who applied to the psychiatry outpatient clinic and 50 age- and sex-matched healthy controls were compared.

Results: It was determined that the mean monocyte values of the OCD group were significantly higher than the healthy group (p =0,001). Neutrophil values (p =0,013) and calculated MLR values (p =0,003) of the OCD group were found to be significantly higher than the healthy group. The MLR optimal cutoff value was 6, the sensitivity and spesificity for the diagnosis of OCD was %12 and %98, respectively in the ROC curve analyses.

Conclusion: It has been demonstrated that MLR and the monocyte levels may be important in predicting the diagnosis of OCD. More clinical studies are needed on this subject.