Hemolytic uremic syndrome is characterized by the manifestation of hemolytic anemia, thrombocytopenia and acute renal failure. It is the one of the most common cause of acute renal failure in infant and children. Microvascular occlusive outgoing with thrombotic microangiopathy frequently with capillaries and less often with arterial is underlying pathology. In this article, we presented a 7-month-old boy with the complaints of fever, bloody diarrhea, vomiting, darkening of urine color and anuria. As a result of peritoneal dialysis in a duration of 10 days totally 240 seance, patient was get off from anuria. This case was reported to emphasize the patients with Hemolytic uremic syndrome should be continued peritoneal dialysis until get off anuria.