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Fırat Tıp Dergisi |
2009, Cilt 14, Sayı 3, Sayfa(lar) 167-170 |
[ Turkish ] [ Tam Metin ] [ PDF ] |
Effects of Electroconvulsive Therapy on Sympathetic Skin Responses in Patients with Major Depression |
Caner Feyzi DEMİR1, Rabia BİLİCİ2, Hasan Hüseyin ÖZDEMİR3, Said BERİLGEN3 |
1Elazığ Eğitim ve Araştırma Hastanesi, Nöroloji Anabilim Dalı, ELAZIĞ, Türkiye 2Elazığ Ruh ve Sinir Hastalıkları Hastanesi, Psikiyatri Anabilim Dalı, ELAZIĞ, Türkiye 3Fırat Üniversitesi Eğitim ve Araştırma Hastanesi, Nöroloji Anabilim Dalı, ELAZIĞ, Türkiye |
Objective: Depressed patients frequently complain about vegetative symptoms. The relation between depression and disturbances of autonomic
regulation has been recognised for a long time. The aim of this study was to investigate whether sympathetic skin responses (SSRs) were affected by
electroconvulsive therapy (ECT) in patients with major depression.
Materials and Methods: In our study we examined 40 patients diagnosed with major depression who would take ECT during a course of treatment
and 30 age-matched healthy subjects. Sympathetic skin responses were assesed on the same day before and after the ECT. Pre-ECT, post-ECT, and
control groups' measurements of SSR were compared by non-parametric tests.
Results: The mean post-ECT latency of SSR (1.25±0.11 ms) was statistically significantly different (p <0.05) compared with pre-ECT latency of
SSR (1.26± 0.11 ms) in patients with major depression. This result demonstrates a relation between SSR and ECT in patients with major depression.
However there was no significant difference in SSR latency between patients (pre-ECT and post-ECT) and controls (1.22±0.08 ms). There was no
statistically difference also in SSR amplitude among three groups.
Conclusion: Data reported in this article support that activation of sympathetic system by ECT treatment does not have a major efficacy in patients
with major depression. More studies are needed to evaluate the effects of depression treatment with ECT on SSR.
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